The Hypertension Clinic

Links

Selected Links:

Hypertension Canada

Hypertension Canada – page for healthcare professionals

Hypertension Canada – page for the general public

Canadian Hypertension Education Program

The DASH Diet to lower high blood pressure

Selected Articles (click on each article, to download the PDF):

Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study: a randomised trial against atenolol (LIFE, 2002).

Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic. The antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT, 2002).

Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm: a multicentre randomised controlled trial (ASCOT-BPLA, 2005).

Treatment of hypertension in patients 80 years of age or older (HYVET, 2008).

Prognostic value of blood pressure in patients with high vascular risk in the Ongoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial study (Ontarget, 2009).

The 2013 Canadian Hypertension Education Program recommendations for blood pressure measurement, diagnosis, assessment of risk, prevention, and treatment of hypertension (CHEP CJC, 2013).

2014 Evidence-based guideline for the management of high blood pressure in adults report from the panel members appointed to the eighth Joint National Committee (JNC 8, 2013).

Selected Publications List:

1. Kuyper L, Khan NA. Atenolol versus non-Atenolol Beta-blockers for the Treatment of Hypertension: A Meta Analysis. CJC (accepted).

2. Khan NA, Herman RJ, Quinn RR, Rabkin SW, Ravani P, Tobe SW, Feldman RD, Wijeysundera HC, Padwal RS; Canadian Hypertension Education Program. Renal denervation therapy for the treatment of resistant hypertension: a position statement by the canadian hypertension education program. Can J Cardiol. 2014 Jan;30(1):16-21. doi: 10.1016/j.cjca.2013.07.008. Epub 2013 Oct 23. PubMed PMID: 24269056.

3: Rabi DM, Padwal R, Tobe SW, Gilbert RE, Leiter LA, Quinn RR, Khan N; Canadian Hypertensive Education Program; Canadian Diabetes Association. Risks and benefits of intensive blood pressure lowering in patients with type 2 diabetes. CMAJ. 2013 Aug 6;185(11):963-7. doi: 10.1503/cmaj.120112. Epub 2013 Jun 3. Review. PubMed PMID: 23734033; PubMed Central PMCID: PMC3735744.

4: Hackam DG, Quinn RR, Ravani P, Rabi DM, Dasgupta K, Daskalopoulou SS, Khan NA,et. al. The 2013 Canadian Hypertension Education Program recommendations for blood pressure measurement, diagnosis, assessment of risk, prevention, and treatment of hypertension. Can J Cardiol. 2013 May;29(5):528-42. doi: 10.1016/j.cjca.2013.01.005. Epub 2013 Mar 29. PubMed PMID: 23541660.

5: Quan H, Chen G, Tu K, Bartlett G, Butt DA, Campbell NR, Hemmelgarn BR, Hill MD, Johansen H, Khan N, Lix LM, Smith M, Svenson L, Walker RL, Wielgosz A, McAlister FA; Hypertension Outcome and Surveillance Team. Outcomes among 3.5 million newly diagnosed hypertensive Canadians. Can J Cardiol. 2013 May;29(5):592-7. doi: 10.1016/j.cjca.2012.12.016. Epub 2013 Mar 5. PubMed PMID: 23465341.

6: Quan H, Chen G, Walker RL, Wielgosz A, Dai S, Tu K, Campbell NR, Hemmelgarn BR, Hill MD, Johansen H, McAlister FA, Khan N; Hypertension Outcome and Surveillance Team. Incidence, cardiovascular complications and mortality of hypertension by sex and ethnicity. Heart. 2013 May;99(10):715-21. doi: 10.1136/heartjnl-2012-303152. Epub 2013 Feb 12. PubMed PMID: 23403406.

7: Daskalopoulou SS, Khan NA, et. al. The 2012 Canadian hypertension education program recommendations for the management of hypertension: blood pressure measurement, diagnosis, assessment of risk, and therapy. Can J Cardiol. 2012 May;28(3):270-87. doi: 10.1016/j.cjca.2012.02.018. Review. PubMed PMID: 22595447.

8: Tobe SW, Poirier L, Tremblay G, Lindsay P, Reid D, Campbell NR, Khan N, Quinn RR, Rabi D; Canadian Hypertension Education Program. Challenges and scientific considerations in hypertension management reflected in the 2012 recommendations of the Canadian Hypertension Education Program. Open Med. 2012 Oct 16;6(4):e127-33. Print 2012. PubMed PMID: 23687527; PubMed Central PMCID: PMC3654508.

9: Walker RL, Chen G, Campbell NR, McAlister FA, Quan H, Tu K, Khan NA, Hemmelgarn BR; Canadian Hypertension Education Program Outcomes Research Task Force. Canadian provincial trends in antihypertensive drug prescriptions between 1996 and 2006. Can J Cardiol. 2011 Jul-Aug;27(4):461-7. doi: 10.1016/j.cjca.2010.12.071. Epub 2011 Jun 2. English, French. PubMed PMID: 21640546.

10: McAlister FA, Herman RJ, Khan NA, Rabkin SW, Campbell N; Canadian Hypertension Education Program. Putting ACCOMPLISH into context: management of hypertension in 2010. CMAJ. 2010 Oct 19;182(15):1600-1. doi: 10.1503/cmaj.092142. Epub 2010 Sep 13. PubMed PMID: 20837685; PubMed Central PMCID: PMC2952002.

11: Quan H, Khan N, Hemmelgarn BR, Tu K, Chen G, Campbell N, Hill MD, Ghali WA, McAlister FA; Hypertension Outcome and Surveillance Team of the Canadian Hypertension Education Programs. Validation of a case definition to define hypertension using administrative data. Hypertension. 2009 Dec;54(6):1423-8. doi: 10.1161/HYPERTENSIONAHA.109.139279. Epub 2009 Oct 26. PubMed PMID: 19858407.